Entity Details

Primary name HIPK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QZR5
EntryNameHIPK2_MOUSE
FullNameHomeodomain-interacting protein kinase 2
TaxID10090
Evidenceevidence at protein level
Length1196
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesHipk2

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001934 positive regulation of protein phosphorylation
GO:0003714 transcription corepressor activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007224 smoothened signaling pathway
GO:0007628 adult walking behavior
GO:0008284 positive regulation of cell population proliferation
GO:0008344 adult locomotory behavior
GO:0009952 anterior/posterior pattern specification
GO:0010842 retina layer formation
GO:0016604 nuclear body
GO:0016605 PML body
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030182 neuron differentiation
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0032092 positive regulation of protein binding
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043388 positive regulation of DNA binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0046332 SMAD binding
GO:0046790 virion binding
GO:0048596 embryonic camera-type eye morphogenesis
GO:0050882 voluntary musculoskeletal movement
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0060235 lens induction in camera-type eye
GO:0060395 SMAD protein signal transduction
GO:0061072 iris morphogenesis
GO:0090575 RNA polymerase II transcription regulator complex
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

Show/Hide Table