Entity Details

Primary name SH2D3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QZS8
EntryNameSH2D3_MOUSE
FullNameSH2 domain-containing protein 3C
TaxID10090
Evidenceevidence at protein level
Length854
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesSh2d3c

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0030424 axon
GO:0032587 ruffle membrane
GO:0033138 positive regulation of peptidyl-serine phosphorylation

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domainDomainDomain
IPR023578 Ras guanine nucleotide exchange factor domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamilyFamilyHomologous superfamily
IPR044102 SHEP1/BCAR3/NSP1, SH2 domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SH2D3_MOUSECASL_MOUSEDIP20956287 details