Entity Details

Primary name ZEB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9R0G7
EntryNameZEB2_MOUSE
FullNameZinc finger E-box-binding homeobox 2
TaxID10090
Evidenceevidence at protein level
Length1215
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesZeb2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001755 neural crest cell migration
GO:0001756 somitogenesis
GO:0001843 neural tube closure
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0021540 corpus callosum morphogenesis
GO:0021766 hippocampus development
GO:0021846 cell proliferation in forebrain
GO:0021957 corticospinal tract morphogenesis
GO:0030177 positive regulation of Wnt signaling pathway
GO:0043507 positive regulation of JUN kinase activity
GO:0043565 sequence-specific DNA binding
GO:0045636 positive regulation of melanocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048023 positive regulation of melanin biosynthetic process
GO:0048066 developmental pigmentation
GO:0048598 embryonic morphogenesis
GO:0048668 collateral sprouting
GO:0048856 anatomical structure development
GO:0050772 positive regulation of axonogenesis
GO:0061373 mammillary axonal complex development
GO:0070412 R-SMAD binding
GO:0097324 melanocyte migration
GO:1902748 positive regulation of lens fiber cell differentiation
GO:1903056 regulation of melanosome organization

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR008598 Drought induced 19 protein type, zinc-binding domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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