Entity Details

Primary name AT2B2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9R0K7
EntryNameAT2B2_MOUSE
FullNamePlasma membrane calcium-transporting ATPase 2
TaxID10090
Evidenceevidence at protein level
Length1198
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesAtp2b2

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0005388 P-type calcium transporter activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006996 organelle organization
GO:0007595 lactation
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0008022 protein C-terminus binding
GO:0008361 regulation of cell size
GO:0016324 apical plasma membrane
GO:0019829 ATPase-coupled cation transmembrane transporter activity
GO:0021549 cerebellum development
GO:0021692 cerebellar Purkinje cell layer morphogenesis
GO:0021702 cerebellar Purkinje cell differentiation
GO:0021707 cerebellar granule cell differentiation
GO:0030165 PDZ domain binding
GO:0030182 neuron differentiation
GO:0030425 dendrite
GO:0030899 calcium-dependent ATPase activity
GO:0032809 neuronal cell body membrane
GO:0035254 glutamate receptor binding
GO:0040011 locomotion
GO:0042428 serotonin metabolic process
GO:0042472 inner ear morphogenesis
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0045121 membrane raft
GO:0045299 otolith mineralization
GO:0046068 cGMP metabolic process
GO:0048167 regulation of synaptic plasticity
GO:0048839 inner ear development
GO:0050808 synapse organization
GO:0050885 neuromuscular process controlling balance
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051928 positive regulation of calcium ion transport
GO:0060088 auditory receptor cell stereocilium organization
GO:0060113 inner ear receptor cell differentiation
GO:0090102 cochlea development
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0098839 postsynaptic density membrane
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099059 integral component of presynaptic active zone membrane
GO:0099061 integral component of postsynaptic density membrane
GO:1905056 P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration
GO:1905059 P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR006408 P-type ATPase, subfamily IIBFamilyFamily
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR022141 Plasma membrane calcium transporting P-type ATPase, C-terminalDomainDomain
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR030322 Plasma membrane calcium-transporting ATPase 2FamilyFamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AT2B2_MOUSEPRIO_MOUSEBioGRID15146195 details
AT2B2_MOUSENEB2_MOUSEBioGRID28634551 30562941 details