Entity Details

Primary name CRY2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9R194
EntryNameCRY2_MOUSE
FullNameCryptochrome-2
TaxID10090
Evidenceevidence at protein level
Length592
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesCry2

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006606 protein import into nucleus
GO:0007623 circadian rhythm
GO:0009416 response to light stimulus
GO:0009881 photoreceptor activity
GO:0014823 response to activity
GO:0016607 nuclear speck
GO:0018298 protein-chromophore linkage
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0019915 lipid storage
GO:0032515 negative regulation of phosphoprotein phosphatase activity
GO:0032868 response to insulin
GO:0032922 circadian regulation of gene expression
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045892 negative regulation of transcription, DNA-templated
GO:0071949 FAD binding
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway
GO:2000850 negative regulation of glucocorticoid secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR005101 Cryptochrome/DNA photolyase, FAD-binding domainDomainDomain
IPR006050 DNA photolyase, N-terminalDomainDomain
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamilyFamilyHomologous superfamily
IPR036155 Cryptochrome/photolyase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
CRY2_MOUSEBMAL1_MOUSEBioGRID, DIP, IntAct, UniProt14701732 16717091 20832105 20840750 23555304 24737000 26562092 details
CRY2_MOUSEPER2_MOUSEBioGRID, DIP, IntAct, MINT, UniProt14701732 20840750 22170608 23079727 23503662 23555304 24737000 25127877 26903623 details
CRY2_MOUSECLOCK_MOUSEBioGRID, IntAct14701732 16717091 23555304 details
CRY2_MOUSEPER1_MOUSEBioGRID, DIP, IntAct14701732 23555304 24737000 details
CRY2_MOUSEBHE41_MOUSEIntAct23555304 details
CRY2_MOUSEBHE40_HUMANIntAct23555304 details
CRY2_MOUSE2A5D_HUMANIntAct23555304 details
CRY2_MOUSE2A5E_HUMANIntAct23555304 details
CRY2_MOUSE2AAB_HUMANIntAct23555304 details
CRY2_MOUSENPAS2_HUMANIntAct23555304 details
CRY2_MOUSEEZH2_HUMANIntAct23555304 details
CRY2_MOUSEFBXL3_HUMANBioGRID, DIP, IntAct17463251 23503662 details
CRY2_MOUSECSK22_HUMANDIP26562092 details
CRY2_MOUSECSK2B_HUMANDIP26562092 details
CRY2_MOUSECSK21_HUMANDIP26562092 details
CRY2_MOUSEFBXL3_MOUSEBioGRID, IntAct17462724 23452855 23452856 23503662 30655559 details
CRY2_MOUSEFXL21_MOUSEIntAct23452855 23452856 details
CRY2_MOUSEKC1A_MOUSEDIP21179498 details
CRY2_MOUSEMK01_MOUSEDIP21179498 details
CRY2_MOUSEGCR_MOUSEDIP22170608 details
CRY2_MOUSEPER1_HUMANBioGRID, DIP23503662 details
CRY2_MOUSECIART_MOUSEDIP24736997 details
CRY2_MOUSECSK2B_MOUSEDIP26562092 details
CRY2_MOUSECRY1_MOUSEBioGRID14701732 details
CRY2_MOUSEPER3_MOUSEBioGRID14701732 15689618 details
CRY2_MOUSEIMA1_MOUSEBioGRID15689618 details
CRY2_MOUSEIMA3_MOUSEBioGRID15689618 details
CRY2_MOUSEIMA7_MOUSEBioGRID15689618 details
CRY2_MOUSEUBP2_MOUSEBioGRID23213472 details
CRY2_MOUSETLK2_HUMANBioGRID30655559 details