Entity Details

Primary name STK11_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WTK7
EntryNameSTK11_MOUSE
FullNameSerine/threonine-protein kinase STK11
TaxID10090
Evidenceevidence at protein level
Length436
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesStk11

GO terms

Show/Hide Table
GOName
GO:0000287 magnesium ion binding
GO:0001558 regulation of cell growth
GO:0001894 tissue homeostasis
GO:0001944 vasculature development
GO:0002039 p53 binding
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006470 protein dephosphorylation
GO:0006914 autophagy
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0007409 axonogenesis
GO:0008285 negative regulation of cell population proliferation
GO:0010212 response to ionizing radiation
GO:0010508 positive regulation of autophagy
GO:0016020 membrane
GO:0030010 establishment of cell polarity
GO:0030111 regulation of Wnt signaling pathway
GO:0030275 LRR domain binding
GO:0030295 protein kinase activator activity
GO:0030308 negative regulation of cell growth
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032147 activation of protein kinase activity
GO:0032991 protein-containing complex
GO:0033993 response to lipid
GO:0042593 glucose homeostasis
GO:0043276 anoikis
GO:0044877 protein-containing complex binding
GO:0045059 positive thymic T cell selection
GO:0045722 positive regulation of gluconeogenesis
GO:0046777 protein autophosphorylation
GO:0048814 regulation of dendrite morphogenesis
GO:0050772 positive regulation of axonogenesis
GO:0050852 T cell receptor signaling pathway
GO:0051645 Golgi localization
GO:0051896 regulation of protein kinase B signaling
GO:0060070 canonical Wnt signaling pathway
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0071493 cellular response to UV-B
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097484 dendrite extension
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1900182 positive regulation of protein localization to nucleus
GO:1901610 positive regulation of vesicle transport along microtubule
GO:1904262 negative regulation of TORC1 signaling

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Membrane
Mitochondrion
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR039154 Serine/Threonine kinase LKB1, catalytic domainDomainDomain

Diseases

Show/Hide Table