Entity Details

Primary name BMAL1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WTL8
EntryNameBMAL1_MOUSE
FullNameAryl hydrocarbon receptor nuclear translocator-like protein 1
TaxID10090
Evidenceevidence at protein level
Length632
SequenceStatuscomplete
DateCreated2003-08-15
DateModified2021-06-02

Ontological Relatives

GenesArntl

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0007283 spermatogenesis
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0016604 nuclear body
GO:0016605 PML body
GO:0017162 aryl hydrocarbon receptor binding
GO:0032007 negative regulation of TOR signaling
GO:0032922 circadian regulation of gene expression
GO:0033391 chromatoid body
GO:0034751 aryl hydrocarbon receptor complex
GO:0042176 regulation of protein catabolic process
GO:0042634 regulation of hair cycle
GO:0042753 positive regulation of circadian rhythm
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050767 regulation of neurogenesis
GO:0050796 regulation of insulin secretion
GO:0051726 regulation of cell cycle
GO:0051775 response to redox state
GO:0051879 Hsp90 protein binding
GO:0060137 maternal process involved in parturition
GO:0070888 E-box binding
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090403 oxidative stress-induced premature senescence
GO:0120163 negative regulation of cold-induced thermogenesis
GO:0140297 DNA-binding transcription factor binding
GO:1901985 positive regulation of protein acetylation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000074 regulation of type B pancreatic cell development
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway
GO:2000772 regulation of cellular senescence
GO:2001016 positive regulation of skeletal muscle cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR001067 Nuclear translocatorFamilyFamily
IPR001610 PAC motifRepeatRepeat
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013767 PAS foldDomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
BMAL1_MOUSESHC1_MOUSEIntAct15102471 details
BMAL1_MOUSECLOCK_MOUSEBioGRID, DIP, IntAct, MINT, UniProt14701732 16606840 16717091 16777965 17347670 18075593 18662546 18662547 20211142 20832105 20840750 21113167 22441692 22653727 23555304 23735699 24737000 25961797 26323038 26562092 28388406 30683868 9704006 details
BMAL1_MOUSEPER2_MOUSEBioGRID, DIP, IntAct14701732 16717091 16777965 18430226 20832105 21113167 21680841 22274616 26903623 details
BMAL1_MOUSECRY1_MOUSEBioGRID, DIP, IntAct14701732 15226430 16717091 16777965 18075593 18430226 20832105 21966515 23555304 24737000 25127877 25961797 26562092 details
BMAL1_MOUSESIR1_HUMANIntAct18662547 details
BMAL1_MOUSEHLF_MOUSEIntAct9704006 details
BMAL1_MOUSEHIF1A_HUMANBioGRID, IntAct9704006 details
BMAL1_MOUSECRY2_MOUSEBioGRID, DIP, IntAct, UniProt14701732 16717091 20832105 20840750 23555304 24737000 26562092 details
BMAL1_MOUSERORG_HUMANIntAct23555304 details
BMAL1_MOUSEWDR5_HUMANIntAct23555304 details
BMAL1_MOUSECSK2B_HUMANDIP, IntAct23555304 26562092 details
BMAL1_MOUSENPAS2_HUMANDIP, IntAct23555304 24737000 details
BMAL1_MOUSEBHE40_HUMANIntAct23555304 details
BMAL1_MOUSEKC1E_MOUSEBioGRID, IntAct21966515 23555304 details
BMAL1_MOUSECIART_HUMANDIP24737000 details
BMAL1_MOUSECLOCK_HUMANDIP24737000 details
BMAL1_MOUSECBP_MOUSEDIP24737000 25961797 details
BMAL1_MOUSEEP300_MOUSEDIP25961797 details
BMAL1_MOUSECSK22_HUMANDIP26562092 details
BMAL1_MOUSECSK21_HUMANDIP26562092 details
BMAL1_MOUSERNF14_MOUSEBioGRID, IntAct20211142 details
BMAL1_MOUSEEPAS1_MOUSEBioGRID20211142 details
BMAL1_MOUSEHIF1A_MOUSEBioGRID20211142 9704006 details
BMAL1_MOUSENECD_MOUSEBioGRID17826745 details
BMAL1_MOUSESIR1_MOUSEBioGRID, IntAct18662546 18662547 details
BMAL1_MOUSEPARP1_MOUSEIntAct20832105 details
BMAL1_MOUSEPP1A_MOUSEIntAct23555304 details
BMAL1_MOUSENPAS2_MOUSEMINT23735699 details
BMAL1_MOUSEKMT2A_HUMANDIP21113167 details
BMAL1_MOUSECIART_MOUSEDIP24736997 details
BMAL1_MOUSEDDB1_MOUSEDIP26323038 details
BMAL1_MOUSECSK2B_MOUSEDIP26562092 details
BMAL1_MOUSECSK21_MOUSEDIP26562092 details
BMAL1_MOUSEPER1_MOUSEBioGRID14701732 16717091 21680841 21966515 details
BMAL1_MOUSEPER3_MOUSEBioGRID14701732 details
BMAL1_MOUSEEZH2_MOUSEBioGRID16717091 details
BMAL1_MOUSEUBP2_MOUSEBioGRID21966515 23213472 details
BMAL1_MOUSERAE1L_MOUSEBioGRID30683868 details
BMAL1_MOUSENUP98_MOUSEBioGRID30683868 details