Entity Details

Primary name VAX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WTP9
EntryNameVAX2_MOUSE
FullNameVentral anterior homeobox 2
TaxID10090
Evidenceevidence at protein level
Length292
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesVax2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007409 axonogenesis
GO:0007417 central nervous system development
GO:0007601 visual perception
GO:0009950 dorsal/ventral axis specification
GO:0016055 Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0030900 forebrain development
GO:0031490 chromatin DNA binding
GO:0043010 camera-type eye development
GO:0048048 embryonic eye morphogenesis
GO:0060041 retina development in camera-type eye
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain
IPR033021 Ventral anterior homeobox 2FamilyFamily

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
VAX2_MOUSEGMEB2_MOUSEBioGRID, IntAct20211142 details
VAX2_MOUSESIX6_MOUSEBioGRID, IntAct20211142 details
VAX2_MOUSERFXK_MOUSEBioGRID, IntAct20211142 details
VAX2_MOUSEPAX6_MOUSEBioGRID, IntAct20211142 details
VAX2_MOUSETF2AA_MOUSEBioGRID, IntAct20211142 details