Entity Details

Primary name PRKRA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WTX2
EntryNamePRKRA_MOUSE
FullNameInterferon-inducible double-stranded RNA-dependent protein kinase activator A
TaxID10090
Evidenceevidence at protein level
Length313
SequenceStatuscomplete
DateCreated2006-02-21
DateModified2021-06-02

Ontological Relatives

GenesPrkra

GO terms

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GOName
GO:0003725 double-stranded RNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0008047 enzyme activator activity
GO:0008284 positive regulation of cell population proliferation
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030422 production of siRNA involved in RNA interference
GO:0031054 pre-miRNA processing
GO:0034599 cellular response to oxidative stress
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0042473 outer ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043583 ear development
GO:0048471 perinuclear region of cytoplasm
GO:0048705 skeletal system morphogenesis
GO:0050821 protein stabilization
GO:0070578 RISC-loading complex
GO:0070883 pre-miRNA binding
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR014720 Double-stranded RNA-binding domainDomainDomain
IPR032478 Staufen, C-terminalDomainDomain
IPR033363 Interferon-inducible double-stranded RNA-dependent protein kinase activator AFamilyFamily
IPR044465 PRKRA, first double-stranded RNA binding domainDomainDomain
IPR044466 PRKRA, second double-stranded RNA binding domainDomainDomain
IPR044467 PRKRA, third double-stranded RNA binding domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PRKRA_MOUSEOTUD4_HUMANBioGRID31138677 details