Entity Details

Primary name CRADD_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88843
EntryNameCRADD_MOUSE
FullNameDeath domain-containing protein CRADD
TaxID10090
Evidenceevidence at protein level
Length199
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesCradd

GO terms

Show/Hide Table
GOName
GO:0002020 protease binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0030674 protein-macromolecule adaptor activity
GO:0043065 positive regulation of apoptotic process
GO:0070513 death domain binding
GO:0071260 cellular response to mechanical stimulus
GO:0097190 apoptotic signaling pathway
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR001315 CARD domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR037926 CRADD, Death domainDomainDomain
IPR037939 Death domain-containing protein CRADDFamilyFamily
IPR042148 RAIDD, CARD domainDomainDomain

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CRADD_MOUSERIPK1_MOUSEBioGRID11978827 details
CRADD_MOUSECASP2_MOUSEBioGRID11978827 details