Entity Details

Primary name SNX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WV80
EntryNameSNX1_MOUSE
FullNameSorting nexin-1
TaxID10090
Evidenceevidence at protein level
Length522
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesSnx1

GO terms

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GOName
GO:0005154 epidermal growth factor receptor binding
GO:0005158 insulin receptor binding
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006886 intracellular protein transport
GO:0010008 endosome membrane
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030904 retromer complex
GO:0030905 retromer, tubulation complex
GO:0031175 neuron projection development
GO:0031623 receptor internalization
GO:0031901 early endosome membrane
GO:0031982 vesicle
GO:0032991 protein-containing complex
GO:0034498 early endosome to Golgi transport
GO:0035091 phosphatidylinositol binding
GO:0042147 retrograde transport, endosome to Golgi
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043197 dendritic spine
GO:0043231 intracellular membrane-bounded organelle
GO:0045732 positive regulation of protein catabolic process
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0072673 lamellipodium morphogenesis
GO:0098793 presynapse
GO:0098999 extrinsic component of postsynaptic endosome membrane
GO:0099092 postsynaptic density, intracellular component
GO:1990459 transferrin receptor binding
GO:1990460 leptin receptor binding

Subcellular Location

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Subcellular Location
Cell projection
Early endosome membrane
Endosome membrane
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001683 Phox homologyDomainDomain
IPR005329 Sorting nexin, N-terminalDomainDomain
IPR015404 Sorting nexin Vps5-like, C-terminalDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR028660 Sorting nexin-1FamilyFamily
IPR034901 Sorting Nexin 1, PX domainDomainDomain
IPR036871 PX domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SNX1_MOUSEIKKB_MOUSEIntAct15102471 details
SNX1_MOUSEVPS35_MOUSEBioGRID18656452 32325033 details