Entity Details

Primary name SGK1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WVC6
EntryNameSGK1_MOUSE
FullNameSerine/threonine-protein kinase Sgk1
TaxID10090
Evidenceevidence at protein level
Length431
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesSgk1

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006883 cellular sodium ion homeostasis
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007019 microtubule depolymerization
GO:0007616 long-term memory
GO:0008542 visual learning
GO:0010765 positive regulation of sodium ion transport
GO:0015459 potassium channel regulator activity
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0030307 positive regulation of cell growth
GO:0031115 negative regulation of microtubule polymerization
GO:0032869 cellular response to insulin stimulus
GO:0032880 regulation of protein localization
GO:0035556 intracellular signal transduction
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0043402 glucocorticoid mediated signaling pathway
GO:0043423 3-phosphoinositide-dependent protein kinase binding
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048812 neuron projection morphogenesis
GO:0050775 positive regulation of dendrite morphogenesis
GO:0051726 regulation of cell cycle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1904045 cellular response to aldosterone

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Endoplasmic reticulum membrane
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain

Diseases

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