Entity Details

Primary name JIP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9WVI9
EntryNameJIP1_MOUSE
FullNameC-Jun-amino-terminal kinase-interacting protein 1
TaxID10090
Evidenceevidence at protein level
Length707
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesMapk8ip1

GO terms

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GOName
GO:0005078 MAP-kinase scaffold activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0007258 JUN phosphorylation
GO:0008432 JUN kinase binding
GO:0016020 membrane
GO:0016192 vesicle-mediated transport
GO:0019894 kinesin binding
GO:0019901 protein kinase binding
GO:0030424 axon
GO:0030425 dendrite
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0031966 mitochondrial membrane
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0043508 negative regulation of JUN kinase activity
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0044297 cell body
GO:0044302 dentate gyrus mossy fiber
GO:0045202 synapse
GO:0046328 regulation of JNK cascade
GO:0046329 negative regulation of JNK cascade
GO:0046330 positive regulation of JNK cascade
GO:0048471 perinuclear region of cytoplasm
GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Mitochondrion membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035638 JIP1, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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