Entity Details

Primary name GDF15_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z0J7
EntryNameGDF15_MOUSE
FullNameGrowth/differentiation factor 15
TaxID10090
Evidenceevidence at protein level
Length303
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesGdf15

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002023 reduction of food intake in response to dietary excess
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0008083 growth factor activity
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 BMP signaling pathway
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
GO:0040015 negative regulation of multicellular organism growth
GO:0042803 protein homodimerization activity
GO:0043410 positive regulation of MAPK cascade
GO:0051897 positive regulation of protein kinase B signaling
GO:0060395 SMAD protein signal transduction
GO:0060400 negative regulation of growth hormone receptor signaling pathway
GO:0070700 BMP receptor binding
GO:1901741 positive regulation of myoblast fusion

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink