Entity Details

Primary name SUFU_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z0P7
EntryNameSUFU_MOUSE
FullNameSuppressor of fused homolog
TaxID10090
Evidenceevidence at protein level
Length484
SequenceStatuscomplete
DateCreated2005-03-29
DateModified2021-06-02

Ontological Relatives

GenesSufu

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001843 neural tube closure
GO:0001947 heart looping
GO:0003281 ventricular septum development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005929 cilium
GO:0007224 smoothened signaling pathway
GO:0007368 determination of left/right symmetry
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0019901 protein kinase binding
GO:0021513 spinal cord dorsal/ventral patterning
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0035904 aorta development
GO:0042994 cytoplasmic sequestering of transcription factor
GO:0043588 skin development
GO:0045879 negative regulation of smoothened signaling pathway
GO:0060976 coronary vasculature development
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR007768 Suppressor of fusedFamilyFamily
IPR016591 Suppressor of fused, eukaryoticFamilyFamily
IPR020941 Suppressor of fused-like domainDomainDomain
IPR024314 Suppressor of fused C-terminalDomainDomain
IPR037181 Suppressor of fused, N-terminalFamilyHomologous superfamily
IPR038489 Suppressor of fused, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
SUFU_MOUSEGLI1_HUMANBioGRID, IntAct11960000 14611647 26120032 details
SUFU_MOUSELEG3_MOUSEIntAct14611647 details
SUFU_MOUSEPIAS1_MOUSEBioGRID, IntAct14611647 details
SUFU_MOUSEGLI3_HUMANBioGRID, IntAct14611647 details
SUFU_MOUSERN19A_MOUSEBioGRID, IntAct14611647 details
SUFU_MOUSESUFU_MOUSEIntAct14611647 details
SUFU_MOUSENCOA3_MOUSEIntAct14611647 details
SUFU_MOUSEROA1_MOUSEIntAct14611647 details
SUFU_MOUSESETB1_MOUSEIntAct14611647 details
SUFU_MOUSESAP18_MOUSEBioGRID, IntAct14611647 details
SUFU_MOUSEHMGA1_MOUSEIntAct14611647 details
SUFU_MOUSECEBPZ_MOUSEIntAct14611647 details
SUFU_MOUSEPRDX6_MOUSEIntAct14611647 details
SUFU_MOUSELTOR3_MOUSEIntAct14611647 details
SUFU_MOUSEH2AY_MOUSEIntAct14611647 details
SUFU_MOUSEZN219_MOUSEBioGRID, IntAct14611647 details
SUFU_MOUSEH2A1B_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1C_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1D_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1E_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1G_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1I_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1N_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1O_MOUSEBioGRID14611647 details
SUFU_MOUSEH2A1P_MOUSEBioGRID14611647 details
SUFU_MOUSESUH_MOUSEBioGRID14611647 details
SUFU_MOUSEPRDX5_MOUSEBioGRID14611647 details
SUFU_MOUSESAP18_HUMANBioGRID11960000 14611647 details
SUFU_MOUSESIN3A_MOUSEBioGRID11960000 details
SUFU_MOUSEGLI1_MOUSEBioGRID10531011 16316410 21076395 24854174 details
SUFU_MOUSEGLI2_MOUSEBioGRID10531011 20463034 details
SUFU_MOUSEGLI3_MOUSEBioGRID10531011 20463034 29515120 details
SUFU_MOUSEGLI2_HUMANBioGRID26120032 details
SUFU_MOUSEITCH_MOUSEBioGRID29515120 details