Entity Details

Primary name PDE3A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z0X4
EntryNamePDE3A_MOUSE
FullNamecGMP-inhibited 3',5'-cyclic phosphodiesterase A
TaxID10090
Evidenceevidence at protein level
Length1141
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesPde3a

GO terms

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GOName
GO:0001556 oocyte maturation
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019933 cAMP-mediated signaling
GO:0019934 cGMP-mediated signaling
GO:0040020 regulation of meiotic nuclear division
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0043116 negative regulation of vascular permeability
GO:0043117 positive regulation of vascular permeability
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0046872 metal ion binding
GO:0060282 positive regulation of oocyte development
GO:0071321 cellular response to cGMP
GO:0071560 cellular response to transforming growth factor beta stimulus

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PDE3A_MOUSEAKT1_MOUSEMINT17124499 details
PDE3A_MOUSEKAPCA_MOUSEMINT17124499 details