Entity Details

Primary name SKP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z0Z3
EntryNameSKP2_MOUSE
FullNameS-phase kinase-associated protein 2
TaxID10090
Evidenceevidence at protein level
Length424
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesSkp2

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000209 protein polyubiquitination
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0019005 SCF ubiquitin ligase complex
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 innate immune response
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051607 defense response to virus
GO:0051726 regulation of cell cycle
GO:0070936 protein K48-linked ubiquitination
GO:0071460 cellular response to cell-matrix adhesion
GO:1902916 positive regulation of protein polyubiquitination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001810 F-box domainDomainDomain
IPR006553 Leucine-rich repeat, cysteine-containing subtypeRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036047 F-box-like domain superfamilyFamilyHomologous superfamily

Diseases

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