Entity Details

Primary name PIAS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88907
EntryNamePIAS1_MOUSE
FullNameE3 SUMO-protein ligase PIAS1
TaxID10090
Evidenceevidence at protein level
Length651
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesPias1

GO terms

Show/Hide Table
GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003712 transcription coregulator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007283 spermatogenesis
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008542 visual learning
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0031625 ubiquitin protein ligase binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235 positive regulation of protein sumoylation
GO:0042127 regulation of cell population proliferation
GO:0043066 negative regulation of apoptotic process
GO:0045444 fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051152 positive regulation of smooth muscle cell differentiation
GO:0061665 SUMO ligase activity
GO:0065004 protein-DNA complex assembly

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus
Nucleus speckle

Domains

Show/Hide Table
DomainNameCategoryType
IPR003034 SAP domainDomainDomain
IPR004181 Zinc finger, MIZ-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR023321 PINIT domainDomainDomain
IPR027226 E3 SUMO-protein ligase PIAS1/PIAS3FamilyFamily
IPR036361 SAP domain superfamilyFamilyHomologous superfamily
IPR038654 PINIT domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table