Entity Details

Primary name ARI2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z1K6
EntryNameARI2_MOUSE
FullNameE3 ubiquitin-protein ligase ARIH2
TaxID10090
Evidenceevidence at protein level
Length492
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesArih2

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
GO:0031466 Cul5-RING ubiquitin ligase complex
GO:0031624 ubiquitin conjugating enzyme binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0046872 metal ion binding
GO:0048588 developmental cell growth
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0071425 hematopoietic stem cell proliferation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002867 IBR domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR031126 E3 ubiquitin-protein ligase ARIH2FamilyFamily
IPR031127 E3 ubiquitin ligase RBR familyFamilyFamily
IPR044066 TRIAD supradomainDomainDomain

Diseases

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