Entity Details

Primary name P2RX7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z1M0
EntryNameP2RX7_MOUSE
FullNameP2X purinoceptor 7
TaxID10090
Evidenceevidence at protein level
Length595
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesP2rx7

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0000902 cell morphogenesis
GO:0001530 lipopolysaccharide binding
GO:0001614 purinergic nucleotide receptor activity
GO:0001819 positive regulation of cytokine production
GO:0001845 phagolysosome assembly
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0001934 positive regulation of protein phosphorylation
GO:0004931 extracellularly ATP-gated cation channel activity
GO:0005524 ATP binding
GO:0005639 integral component of nuclear inner membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0006509 membrane protein ectodomain proteolysis
GO:0006649 phospholipid transfer to membrane
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0006884 cell volume homeostasis
GO:0006900 vesicle budding from membrane
GO:0006954 inflammatory response
GO:0007005 mitochondrion organization
GO:0007009 plasma membrane organization
GO:0008219 cell death
GO:0009612 response to mechanical stimulus
GO:0009617 response to bacterium
GO:0009897 external side of plasma membrane
GO:0010033 response to organic substance
GO:0010043 response to zinc ion
GO:0010467 gene expression
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010628 positive regulation of gene expression
GO:0012501 programmed cell death
GO:0014049 positive regulation of glutamate secretion
GO:0014054 positive regulation of gamma-aminobutyric acid secretion
GO:0014070 response to organic cyclic compound
GO:0015267 channel activity
GO:0016020 membrane
GO:0016079 synaptic vesicle exocytosis
GO:0016485 protein processing
GO:0017121 plasma membrane phospholipid scrambling
GO:0019233 sensory perception of pain
GO:0030163 protein catabolic process
GO:0030501 positive regulation of bone mineralization
GO:0031594 neuromuscular junction
GO:0031668 cellular response to extracellular stimulus
GO:0032060 bleb assembly
GO:0032308 positive regulation of prostaglandin secretion
GO:0032496 response to lipopolysaccharide
GO:0032730 positive regulation of interleukin-1 alpha production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032963 collagen metabolic process
GO:0033198 response to ATP
GO:0034405 response to fluid shear stress
GO:0034767 positive regulation of ion transmembrane transport
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0038023 signaling receptor activity
GO:0042098 T cell proliferation
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043085 positive regulation of catalytic activity
GO:0043132 NAD transport
GO:0043409 negative regulation of MAPK cascade
GO:0043410 positive regulation of MAPK cascade
GO:0045202 synapse
GO:0045332 phospholipid translocation
GO:0045778 positive regulation of ossification
GO:0045779 negative regulation of bone resorption
GO:0045794 negative regulation of cell volume
GO:0045821 positive regulation of glycolytic process
GO:0046513 ceramide biosynthetic process
GO:0046931 pore complex assembly
GO:0048705 skeletal system morphogenesis
GO:0048873 homeostasis of number of cells within a tissue
GO:0050714 positive regulation of protein secretion
GO:0050830 defense response to Gram-positive bacterium
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051592 response to calcium ion
GO:0051602 response to electrical stimulus
GO:0051899 membrane depolarization
GO:0051901 positive regulation of mitochondrial depolarization
GO:0070230 positive regulation of lymphocyte apoptotic process
GO:0071359 cellular response to dsRNA
GO:0071407 cellular response to organic cyclic compound
GO:0072593 reactive oxygen species metabolic process
GO:0097191 extrinsic apoptotic signaling pathway
GO:0098793 presynapse
GO:0098794 postsynapse
GO:1904172 positive regulation of bleb assembly

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001429 P2X purinoreceptorFamilyFamily
IPR003050 P2X7 purinoceptorFamilyFamily
IPR027309 P2X purinoreceptor extracellular domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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