Entity Details

Primary name IOD2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z1Y9
EntryNameIOD2_MOUSE
FullNameType II iodothyronine deiodinase
TaxID10090
Evidenceevidence at protein level
Length266
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesDio2

GO terms

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GOName
GO:0004800 thyroxine 5'-deiodinase activity
GO:0006590 thyroid hormone generation
GO:0009409 response to cold
GO:0016021 integral component of membrane
GO:0031625 ubiquitin protein ligase binding
GO:0033798 thyroxine 5-deiodinase activity
GO:0042403 thyroid hormone metabolic process
GO:0042404 thyroid hormone catabolic process
GO:0042446 hormone biosynthetic process
GO:0050873 brown fat cell differentiation
GO:0070460 thyroid-stimulating hormone secretion
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000643 Iodothyronine deiodinaseFamilyFamily
IPR008261 Iodothyronine deiodinase, active siteSiteActive site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink