Entity Details

Primary name CP8B1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88962
EntryNameCP8B1_MOUSE
FullName7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
TaxID10090
Evidenceevidence at protein level
Length500
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesCyp8b1

GO terms

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GOName
GO:0005506 iron ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0006699 bile acid biosynthetic process
GO:0008397 sterol 12-alpha-hydroxylase activity
GO:0016021 integral component of membrane
GO:0020037 heme binding
GO:0033779 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
GO:0045797 positive regulation of intestinal cholesterol absorption

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002403 Cytochrome P450, E-class, group IVFamilyFamily
IPR024204 Cytochrome P450, cholesterol 7-alpha-monooxygenase-typeFamilyFamily
IPR030686 Cytochrome P450 8B1FamilyFamily
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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