Entity Details

Primary name GSDME_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z2D3
EntryNameGSDME_MOUSE
FullNameGasdermin-E
TaxID10090
Evidenceevidence at protein level
Length512
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesGsdme

GO terms

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GOName
GO:0002839 positive regulation of immune response to tumor cell
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007605 sensory perception of sound
GO:0008219 cell death
GO:0008285 negative regulation of cell population proliferation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0022829 wide pore channel activity
GO:0043410 positive regulation of MAPK cascade
GO:0060113 inner ear receptor cell differentiation
GO:0070265 necrotic cell death
GO:0070269 pyroptosis
GO:0071356 cellular response to tumor necrosis factor
GO:0098586 cellular response to virus
GO:0140507 granzyme-mediated programmed cell death signaling pathway
GO:1901612 cardiolipin binding
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR040460 Gasdermin, pore forming domainDomainDomain
IPR041263 Gasdermin, PUB domainDomainDomain
IPR042377 Gasdermin-EFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink