Entity Details

Primary name MECP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z2D6
EntryNameMECP2_MOUSE
FullNameMethyl-CpG-binding protein 2
TaxID10090
Evidenceevidence at protein level
Length484
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesMecp2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000400 four-way junction DNA binding
GO:0000785 chromatin
GO:0000792 heterochromatin
GO:0001662 behavioral fear response
GO:0001666 response to hypoxia
GO:0001964 startle response
GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure
GO:0002087 regulation of respiratory gaseous exchange by nervous system process
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006020 inositol metabolic process
GO:0006342 chromatin silencing
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006541 glutamine metabolic process
GO:0006576 cellular biogenic amine metabolic process
GO:0006641 triglyceride metabolic process
GO:0007052 mitotic spindle organization
GO:0007268 chemical synaptic transmission
GO:0007416 synapse assembly
GO:0007420 brain development
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0007612 learning
GO:0007613 memory
GO:0007616 long-term memory
GO:0008104 protein localization
GO:0008134 transcription factor binding
GO:0008211 glucocorticoid metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0008327 methyl-CpG binding
GO:0008344 adult locomotory behavior
GO:0008542 visual learning
GO:0009791 post-embryonic development
GO:0010385 double-stranded methylated DNA binding
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0016358 dendrite development
GO:0016525 negative regulation of angiogenesis
GO:0016571 histone methylation
GO:0016573 histone acetylation
GO:0019230 proprioception
GO:0019233 sensory perception of pain
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0021549 cerebellum development
GO:0021591 ventricular system development
GO:0030182 neuron differentiation
GO:0031175 neuron projection development
GO:0031490 chromatin DNA binding
GO:0031915 positive regulation of synaptic plasticity
GO:0032048 cardiolipin metabolic process
GO:0032091 negative regulation of protein binding
GO:0032991 protein-containing complex
GO:0033555 multicellular organismal response to stress
GO:0035176 social behavior
GO:0035197 siRNA binding
GO:0035865 cellular response to potassium ion
GO:0040029 regulation of gene expression, epigenetic
GO:0042220 response to cocaine
GO:0042551 neuron maturation
GO:0042826 histone deacetylase binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0044030 regulation of DNA methylation
GO:0045322 unmethylated CpG binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046470 phosphatidylcholine metabolic process
GO:0047485 protein N-terminus binding
GO:0048167 regulation of synaptic plasticity
GO:0048712 negative regulation of astrocyte differentiation
GO:0050807 regulation of synapse organization
GO:0050884 neuromuscular process controlling posture
GO:0050905 neuromuscular process
GO:0051151 negative regulation of smooth muscle cell differentiation
GO:0051570 regulation of histone H3-K9 methylation
GO:0051707 response to other organism
GO:0060079 excitatory postsynaptic potential
GO:0060291 long-term synaptic potentiation
GO:0060999 positive regulation of dendritic spine development
GO:0061000 negative regulation of dendritic spine development
GO:0071317 cellular response to isoquinoline alkaloid
GO:0090063 positive regulation of microtubule nucleation
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:1900114 positive regulation of histone H3-K9 trimethylation
GO:1901953 positive regulation of anterograde dense core granule transport
GO:1901956 positive regulation of retrograde dense core granule transport
GO:1903860 negative regulation of dendrite extension
GO:1903861 positive regulation of dendrite extension
GO:1905492 positive regulation of branching morphogenesis of a nerve
GO:1905643 positive regulation of DNA methylation
GO:1990841 promoter-specific chromatin binding
GO:2000635 negative regulation of primary miRNA processing
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001739 Methyl-CpG DNA bindingDomainDomain
IPR016177 DNA-binding domain superfamilyFamilyHomologous superfamily
IPR017353 Methyl-CpG binding protein MeCP2FamilyFamily

Diseases

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