Entity Details

Primary name LETM1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z2I0
EntryNameLETM1_MOUSE
FullNameMitochondrial proton/calcium exchanger protein
TaxID10090
Evidenceevidence at protein level
Length738
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesLetm1

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0006875 cellular metal ion homeostasis
GO:0015369 calcium:proton antiporter activity
GO:0016021 integral component of membrane
GO:0034214 protein hexamerization
GO:0042407 cristae formation
GO:0043022 ribosome binding
GO:0046872 metal ion binding
GO:0051260 protein homooligomerization
GO:0051560 mitochondrial calcium ion homeostasis
GO:0051562 negative regulation of mitochondrial calcium ion concentration
GO:0099093 calcium export from the mitochondrion
GO:1900069 regulation of cellular hyperosmotic salinity response

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR011685 LETM1-likeDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR033122 Letm1 ribosome-binding domainDomainDomain
IPR044202 LETM1/MDM38-likeFamilyFamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink