Entity Details

Primary name HDAC5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9Z2V6
EntryNameHDAC5_MOUSE
FullNameHistone deacetylase 5
TaxID10090
Evidenceevidence at protein level
Length1113
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0002076 osteoblast development
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006476 protein deacetylation
GO:0006954 inflammatory response
GO:0007399 nervous system development
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0010629 negative regulation of gene expression
GO:0010830 regulation of myotube differentiation
GO:0010832 negative regulation of myotube differentiation
GO:0016575 histone deacetylation
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0019901 protein kinase binding
GO:0030183 B cell differentiation
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032991 protein-containing complex
GO:0033555 multicellular organismal response to stress
GO:0033558 protein deacetylase activity
GO:0040029 regulation of gene expression, epigenetic
GO:0042113 B cell activation
GO:0042220 response to cocaine
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0043393 regulation of protein binding
GO:0044295 axonal growth cone
GO:0045668 negative regulation of osteoblast differentiation
GO:0045843 negative regulation of striated muscle tissue development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048742 regulation of skeletal muscle fiber development
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051153 regulation of striated muscle cell differentiation
GO:0061333 renal tubule morphogenesis
GO:0071498 cellular response to fluid shear stress
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
GO:0090571 RNA polymerase II transcription repressor complex
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000648 positive regulation of stem cell proliferation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000286 Histone deacetylase familyFamilyFamily
IPR017320 Histone deacetylase class II, eukaryoticFamilyFamily
IPR023696 Ureohydrolase domain superfamilyFamilyHomologous superfamily
IPR023801 Histone deacetylase domainDomainDomain
IPR024643 Histone deacetylase, glutamine rich N-terminal domainDomainDomain
IPR030703 Histone deacetylase 5FamilyFamily
IPR037138 Histone deacetylase domain superfamilyFamilyHomologous superfamily

Diseases

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