Entity Details

Primary name TPP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO89023
EntryNameTPP1_MOUSE
FullNameTripeptidyl-peptidase 1
TaxID10090
Evidenceevidence at protein level
Length562
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesTpp1

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0006508 proteolysis
GO:0007040 lysosome organization
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0008240 tripeptidyl-peptidase activity
GO:0030855 epithelial cell differentiation
GO:0035727 lysophosphatidic acid binding
GO:0042277 peptide binding
GO:0042470 melanosome
GO:0043171 peptide catabolic process
GO:0045121 membrane raft
GO:0045453 bone resorption
GO:0046872 metal ion binding
GO:0050885 neuromuscular process controlling balance
GO:0055037 recycling endosome
GO:0070198 protein localization to chromosome, telomeric region
GO:0120146 sulfatide binding
GO:1905146 lysosomal protein catabolic process

Subcellular Location

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Subcellular Location
Lysosome
Melanosome

Domains

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DomainNameCategoryType
IPR000209 Peptidase S8/S53 domainDomainDomain
IPR015366 Peptidase S53, activation domainDomainDomain
IPR030400 Sedolisin domainDomainDomain
IPR036852 Peptidase S8/S53 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TPP1_MOUSEPOTE1_MOUSEMINT17053789 details
TPP1_MOUSERNF8_MOUSEBioGRID22101936 details