Entity Details

Primary name CDC6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO89033
EntryNameCDC6_MOUSE
FullNameCell division control protein 6 homolog
TaxID10090
Evidenceevidence at protein level
Length562
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesCdc6

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000922 spindle pole
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0006270 DNA replication initiation
GO:0019900 kinase binding
GO:0030071 regulation of mitotic metaphase/anaphase transition
GO:0032467 positive regulation of cytokinesis
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0045171 intercellular bridge
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0051233 spindle midzone
GO:0051301 cell division
GO:0051984 positive regulation of chromosome segregation
GO:0072686 mitotic spindle

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR015163 Cdc6, C-terminalDomainDomain
IPR016314 Cell division protein Cdc6/18FamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR041083 AAA lid domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CDC6_MOUSEH2B2B_MOUSEBioGRID18635963 details
CDC6_MOUSECDK2_MOUSEBioGRID18356301 details