Entity Details

Primary name PDE4A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO89084
EntryNamePDE4A_MOUSE
FullNamecAMP-specific 3',5'-cyclic phosphodiesterase 4A
TaxID10090
Evidenceevidence at protein level
Length844
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesPde4a

GO terms

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GOName
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006198 cAMP catabolic process
GO:0007165 signal transduction
GO:0007608 sensory perception of smell
GO:0010738 regulation of protein kinase A signaling
GO:0016020 membrane
GO:0030552 cAMP binding
GO:0035690 cellular response to drug
GO:0043949 regulation of cAMP-mediated signaling
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0050804 modulation of chemical synaptic transmission
GO:0098685 Schaffer collateral - CA1 synapse

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR023088 3'5'-cyclic nucleotide phosphodiesteraseFamilyFamily
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily
IPR040844 Phosphodiesterase 4 upstream conserved regions (UCR)DomainDomain

Diseases

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Interactions

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