Entity Details

Primary name TIKI2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionA6NFA1
EntryNameTIKI2_HUMAN
FullNameMetalloprotease TIKI2
TaxID9606
Evidenceevidence at protein level
Length517
SequenceStatuscomplete
DateCreated2008-09-02
DateModified2021-06-02

Ontological Relatives

GenesTRABD2B

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005887 integral component of plasma membrane
GO:0006508 proteolysis
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0030178 negative regulation of Wnt signaling pathway
GO:0031301 integral component of organelle membrane
GO:0031334 positive regulation of protein-containing complex assembly
GO:0046872 metal ion binding
GO:1904808 positive regulation of protein oxidation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002816 TraB/PrgY/GumN familyFamilyFamily
IPR040230 Protease TIKI1/2-likeFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TIKI2_HUMANWNT3A_MOUSEIntAct22726442 details
TIKI2_HUMANWNT5A_MOUSEIntAct22726442 details