Entity Details

Primary name MYC_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP01108
EntryNameMYC_MOUSE
FullNameMyc proto-oncogene protein
TaxID10090
Evidenceevidence at protein level
Length439
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesMyc

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000320 re-entry into mitotic cell cycle
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001783 B cell apoptotic process
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002082 regulation of oxidative phosphorylation
GO:0002904 positive regulation of B cell apoptotic process
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005819 spindle
GO:0006006 glucose metabolic process
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006848 pyruvate transport
GO:0006865 amino acid transport
GO:0006879 cellular iron ion homeostasis
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007007 inner mitochondrial membrane organization
GO:0007346 regulation of mitotic cell cycle
GO:0008134 transcription factor binding
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009314 response to radiation
GO:0010332 response to gamma radiation
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016055 Wnt signaling pathway
GO:0016485 protein processing
GO:0016604 nuclear body
GO:0019087 transformation of host cell by virus
GO:0030424 axon
GO:0031625 ubiquitin protein ligase binding
GO:0032091 negative regulation of protein binding
GO:0032204 regulation of telomere maintenance
GO:0032986 protein-DNA complex disassembly
GO:0032991 protein-containing complex
GO:0035457 cellular response to interferon-alpha
GO:0035690 cellular response to drug
GO:0035914 skeletal muscle cell differentiation
GO:0042474 middle ear morphogenesis
GO:0042981 regulation of apoptotic process
GO:0043085 positive regulation of catalytic activity
GO:0043279 response to alkaloid
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043388 positive regulation of DNA binding
GO:0043473 pigmentation
GO:0043565 sequence-specific DNA binding
GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0045656 negative regulation of monocyte differentiation
GO:0045787 positive regulation of cell cycle
GO:0045821 positive regulation of glycolytic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046325 negative regulation of glucose import
GO:0046722 lactic acid secretion
GO:0046983 protein dimerization activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0048147 negative regulation of fibroblast proliferation
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048705 skeletal system morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0051276 chromosome organization
GO:0051782 negative regulation of cell division
GO:0051973 positive regulation of telomerase activity
GO:0060252 positive regulation of glial cell proliferation
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060548 negative regulation of cell death
GO:0070371 ERK1 and ERK2 cascade
GO:0070888 E-box binding
GO:0071456 cellular response to hypoxia
GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation
GO:1901857 positive regulation of cellular respiration
GO:1903862 positive regulation of oxidative phosphorylation
GO:1904672 regulation of somatic stem cell population maintenance
GO:1905643 positive regulation of DNA methylation
GO:2000573 positive regulation of DNA biosynthetic process
GO:2001022 positive regulation of response to DNA damage stimulus
GO:2001171 positive regulation of ATP biosynthetic process
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002418 Transcription regulator MycFamilyFamily
IPR003327 Leucine zipper, MycDomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR012682 Transcription regulator Myc, N-terminalDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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