Entity Details

Primary name NGF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP01139
EntryNameNGF_MOUSE
FullNameBeta-nerve growth factor
TaxID10090
Evidenceevidence at protein level
Length241
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesNgf

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0004857 enzyme inhibitor activity
GO:0005163 nerve growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007422 peripheral nervous system development
GO:0007613 memory
GO:0007623 circadian rhythm
GO:0008021 synaptic vesicle
GO:0008083 growth factor activity
GO:0008191 metalloendopeptidase inhibitor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008289 lipid binding
GO:0008344 adult locomotory behavior
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010628 positive regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0014042 positive regulation of neuron maturation
GO:0019233 sensory perception of pain
GO:0021675 nerve development
GO:0030297 transmembrane receptor protein tyrosine kinase activator activity
GO:0030307 positive regulation of cell growth
GO:0030424 axon
GO:0030425 dendrite
GO:0031175 neuron projection development
GO:0031398 positive regulation of protein ubiquitination
GO:0031904 endosome lumen
GO:0031954 positive regulation of protein autophosphorylation
GO:0032092 positive regulation of protein binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038177 death receptor agonist activity
GO:0038180 nerve growth factor signaling pathway
GO:0043388 positive regulation of DNA binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0044306 neuron projection terminus
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045773 positive regulation of axon extension
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046928 regulation of neurotransmitter secretion
GO:0048666 neuron development
GO:0048672 positive regulation of collateral sprouting
GO:0048812 neuron projection morphogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway
GO:0051402 neuron apoptotic process
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:2000648 positive regulation of stem cell proliferation
GO:2000675 negative regulation of type B pancreatic cell apoptotic process

Subcellular Location

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Subcellular Location
Endosome lumen
Secreted

Domains

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DomainNameCategoryType
IPR002072 Nerve growth factor-relatedDomainDomain
IPR019846 Nerve growth factor conserved siteSiteConserved site
IPR020408 Nerve growth factor-likeFamilyFamily
IPR020425 Nerve growth factor, beta subunitFamilyFamily
IPR020437 Nerve growth factor, beta subunit, mammalianFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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