Entity Details

Primary name INS2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP01326
EntryNameINS2_MOUSE
FullNameInsulin-2
TaxID10090
Evidenceevidence at protein level
Length110
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesIns2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000187 obsolete activation of MAPK activity
GO:0001819 positive regulation of cytokine production
GO:0002020 protease binding
GO:0002674 negative regulation of acute inflammatory response
GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006006 glucose metabolic process
GO:0006521 regulation of cellular amino acid metabolic process
GO:0006953 acute-phase response
GO:0006983 ER overload response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007520 myoblast fusion
GO:0008284 positive regulation of cell population proliferation
GO:0008286 insulin receptor signaling pathway
GO:0010033 response to organic substance
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010750 positive regulation of nitric oxide mediated signal transduction
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014902 myotube differentiation
GO:0016042 lipid catabolic process
GO:0022898 regulation of transmembrane transporter activity
GO:0030141 secretory granule
GO:0032148 activation of protein kinase B activity
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032880 regulation of protein localization
GO:0033861 negative regulation of NAD(P)H oxidase activity
GO:0034774 secretory granule lumen
GO:0042060 wound healing
GO:0042177 negative regulation of protein catabolic process
GO:0042325 regulation of phosphorylation
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0043393 regulation of protein binding
GO:0043410 positive regulation of MAPK cascade
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0045818 negative regulation of glycogen catabolic process
GO:0045821 positive regulation of glycolytic process
GO:0045840 positive regulation of mitotic nuclear division
GO:0045861 negative regulation of proteolysis
GO:0045922 negative regulation of fatty acid metabolic process
GO:0046326 positive regulation of glucose import
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0046631 alpha-beta T cell activation
GO:0050708 regulation of protein secretion
GO:0050709 negative regulation of protein secretion
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050995 negative regulation of lipid catabolic process
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0055089 fatty acid homeostasis
GO:0060070 canonical Wnt signaling pathway
GO:0060266 negative regulation of respiratory burst involved in inflammatory response
GO:0060267 positive regulation of respiratory burst
GO:0062023 collagen-containing extracellular matrix
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1900182 positive regulation of protein localization to nucleus
GO:1902952 positive regulation of dendritic spine maintenance
GO:1903076 regulation of protein localization to plasma membrane
GO:1903427 negative regulation of reactive oxygen species biosynthetic process
GO:1904659 glucose transmembrane transport
GO:1990535 neuron projection maintenance
GO:2000252 negative regulation of feeding behavior

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR004825 InsulinFamilyFamily
IPR016179 Insulin-likeDomainDomain
IPR022352 Insulin familyFamilyFamily
IPR022353 Insulin, conserved siteSiteConserved site
IPR036438 Insulin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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