Entity Details

Primary name IRG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionA6NK06
EntryNameIRG1_HUMAN
FullNameCis-aconitate decarboxylase
TaxID9606
Evidenceevidence at protein level
Length481
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesACOD1

GO terms

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GOName
GO:0002760 positive regulation of antimicrobial humoral response
GO:0005739 mitochondrion
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007566 embryo implantation
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032480 negative regulation of type I interferon production
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
GO:0035458 cellular response to interferon-beta
GO:0045824 negative regulation of innate immune response
GO:0047613 aconitate decarboxylase activity
GO:0050728 negative regulation of inflammatory response
GO:0051607 defense response to virus
GO:0071219 cellular response to molecule of bacterial origin
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071393 cellular response to progesterone stimulus
GO:0072573 tolerance induction to lipopolysaccharide
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR005656 MmgE/PrpDFamilyFamily
IPR036148 MmgE/PrpD superfamilyFamilyHomologous superfamily
IPR042183 MmgE/PrpD superfamily, domain 1FamilyHomologous superfamily
IPR042188 MmgE/PrpD superfamily, domain 2FamilyHomologous superfamily

Diseases

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Interactions

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