Entity Details

Primary name APBB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00213
EntryNameAPBB1_HUMAN
FullNameAmyloid-beta A4 precursor protein-binding family B member 1
TaxID9606
Evidenceevidence at protein level
Length710
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesAPBB1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001540 amyloid-beta binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006302 double-strand break repair
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007165 signal transduction
GO:0007409 axonogenesis
GO:0008134 transcription factor binding
GO:0016607 nuclear speck
GO:0030027 lamellipodium
GO:0030308 negative regulation of cell growth
GO:0030426 growth cone
GO:0031625 ubiquitin protein ligase binding
GO:0042393 histone binding
GO:0043065 positive regulation of apoptotic process
GO:0043967 histone H4 acetylation
GO:0045202 synapse
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050714 positive regulation of protein secretion
GO:0050750 low-density lipoprotein particle receptor binding
GO:0070064 proline-rich region binding

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001202 WW domainDomainDomain
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR039576 Fe65FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
APBB1_HUMANA4_MOUSEMINT11517249 details
APBB1_HUMANELMO1_MOUSEBioGRID29615491 details