Entity Details

Primary name SPT5H_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00267
EntryNameSPT5H_HUMAN
FullNameTranscription elongation factor SPT5
TaxID9606
Evidenceevidence at protein level
Length1087
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesSUPT5H

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0016239 positive regulation of macroautophagy
GO:0019899 enzyme binding
GO:0032044 DSIF complex
GO:0032785 negative regulation of DNA-templated transcription, elongation
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050434 positive regulation of viral transcription
GO:1900364 negative regulation of mRNA polyadenylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR005100 NGN domainDomainDomain
IPR005824 KOWDomainDomain
IPR006645 NusG, N-terminalDomainDomain
IPR008991 Translation protein SH3-like domain superfamilyFamilyHomologous superfamily
IPR014722 Ribosomal protein L2, domain 2FamilyHomologous superfamily
IPR017071 Transcription elongation factor Spt5, eukaryoteFamilyFamily
IPR022581 Spt5 transcription elongation factor, N-terminalDomainDomain
IPR024945 Spt5 C-terminal domainDomainDomain
IPR036735 NusG, N-terminal domain superfamilyFamilyHomologous superfamily
IPR039385 NGN domain, eukaryoticDomainDomain
IPR039659 Transcription elongation factor SPT5FamilyFamily
IPR041973 Spt5, KOW domain repeat 1DomainDomain
IPR041975 Spt5, KOW domain repeat 2DomainDomain
IPR041976 Spt5, KOW domain repeat 3DomainDomain
IPR041977 Spt5, KOW domain repeat 4DomainDomain
IPR041978 Spt5, KOW domain repeat 5DomainDomain
IPR041980 Spt5, KOW domain repeat 6DomainDomain

Diseases

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Interactions

0 interactions

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