Entity Details

Primary name DFFA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00273
EntryNameDFFA_HUMAN
FullNameDNA fragmentation factor subunit alpha
TaxID9606
Evidenceevidence at protein level
Length331
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDFFA

GO terms

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GOName
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006309 apoptotic DNA fragmentation
GO:0019904 protein domain specific binding
GO:0032076 negative regulation of deoxyribonuclease activity
GO:0032991 protein-containing complex
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0044183 protein folding chaperone
GO:0060703 deoxyribonuclease inhibitor activity
GO:0061077 chaperone-mediated protein folding
GO:0070242 thymocyte apoptotic process
GO:1900118 negative regulation of execution phase of apoptosis
GO:1902511 negative regulation of apoptotic DNA fragmentation

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003508 CIDE-N domainDomainDomain
IPR015121 DNA fragmentation factor 45kDa, middle domainDomainDomain
IPR017299 DNA fragmentation factor 45FamilyFamily
IPR027296 DNA fragmentation factor 45kDa, C-terminalFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DFFA_HUMANDFFB_MOUSEMINT22727028 details