Entity Details

Primary name CACB4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00305
EntryNameCACB4_HUMAN
FullNameVoltage-dependent L-type calcium channel subunit beta-4
TaxID9606
Evidenceevidence at protein level
Length520
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCACNB4

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0007268 chemical synaptic transmission
GO:0007528 neuromuscular junction development
GO:0009898 cytoplasmic side of plasma membrane
GO:0045202 synapse
GO:0051899 membrane depolarization
GO:1901385 regulation of voltage-gated calcium channel activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000584 Voltage-dependent calcium channel, L-type, beta subunitFamilyFamily
IPR001452 SH3 domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00243 RanolazineDrugbanksmall molecule
DB00252 PhenytoinDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule
DB00393 NimodipineDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00653 Magnesium sulfateDrugbanksmall molecule
DB00825 LevomentholDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB01118 AmiodaroneDrugbanksmall molecule
DB01388 MibefradilDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB09089 TrimebutineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09232 CilnidipineDrugbanksmall molecule
DB09236 LacidipineDrugbanksmall molecule
DB09238 ManidipineDrugbanksmall molecule
DB11093 Calcium citrateDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB13961 Fish oilDrugbankbiotech
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CACB4_HUMANRIMS3_MOUSEBioGRID26142343 details