Entity Details

Primary name IPO5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00410
EntryNameIPO5_HUMAN
FullNameImportin-5
TaxID9606
Evidenceevidence at protein level
Length1097
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesIPO5

GO terms

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GOName
GO:0003723 RNA binding
GO:0005095 GTPase inhibitor activity
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006606 protein import into nucleus
GO:0006607 NLS-bearing protein import into nucleus
GO:0006610 ribosomal protein import into nucleus
GO:0008139 nuclear localization sequence binding
GO:0016020 membrane
GO:0016032 viral process
GO:0031267 small GTPase binding
GO:0042307 positive regulation of protein import into nucleus
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0061608 nuclear import signal receptor activity
GO:0071230 cellular response to amino acid stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000357 HEAT repeatRepeatRepeat
IPR001494 Importin-beta, N-terminal domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR034085 TOG domainDomainDomain
IPR040122 Importin beta familyFamilyFamily
IPR040928 Importin repeatRepeatRepeat
IPR041389 Importin repeat 6RepeatRepeat
IPR041653 Importin repeat 4RepeatRepeat

Diseases

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Interactions

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