Entity Details

Primary name PTN3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2ALK8
EntryNamePTN3_MOUSE
FullNameTyrosine-protein phosphatase non-receptor type 3
TaxID10090
Evidenceevidence at protein level
Length913
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesPtpn3

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0004725 protein tyrosine phosphatase activity
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0006470 protein dephosphorylation
GO:0008092 cytoskeletal protein binding
GO:0009898 cytoplasmic side of plasma membrane
GO:0017080 sodium channel regulator activity
GO:0045930 negative regulation of mitotic cell cycle
GO:0051045 negative regulation of membrane protein ectodomain proteolysis
GO:0051117 ATPase binding
GO:0097421 liver regeneration
GO:0098902 regulation of membrane depolarization during action potential
GO:2000649 regulation of sodium ion transmembrane transporter activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000299 FERM domainDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR012151 Protein-tyrosine phosphatase, non-receptor type-3, -4FamilyFamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR041783 PTPN3/4, FERM domain C-lobeDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PTN3_MOUSECD3Z_MOUSEMINT18614237 details