Entity Details

Primary name PSDE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00487
EntryNamePSDE_HUMAN
FullName26S proteasome non-ATPase regulatory subunit 14
TaxID9606
Evidenceevidence at protein level
Length310
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesPSMD14

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0000502 proteasome complex
GO:0000724 double-strand break repair via homologous recombination
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004843 thiol-dependent deubiquitinase
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006521 regulation of cellular amino acid metabolic process
GO:0008237 metallopeptidase activity
GO:0008541 proteasome regulatory particle, lid subcomplex
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016579 protein deubiquitination
GO:0022624 proteasome accessory complex
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031597 cytosolic proteasome complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034774 secretory granule lumen
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043312 neutrophil degranulation
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0045471 response to ethanol
GO:0046872 metal ion binding
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061133 endopeptidase activator activity
GO:0061136 regulation of proteasomal protein catabolic process
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0061578 Lys63-specific deubiquitinase activity
GO:0070122 isopeptidase activity
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070536 protein K63-linked deubiquitination
GO:0070628 proteasome binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000555 JAB1/MPN/MOV34 metalloenzyme domainDomainDomain
IPR024969 Rpn11/EIF3F, C-terminalDomainDomain
IPR035299 26S Proteasome non-ATPase regulatory subunit 14FamilyFamily
IPR037518 MPN domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PSDE_HUMANUBE3A_MOUSEBioGRID31235931 details