Entity Details

Primary name BIN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00499
EntryNameBIN1_HUMAN
FullNameMyc box-dependent-interacting protein 1
TaxID9606
Evidenceevidence at protein level
Length593
SequenceStatuscomplete
DateCreated2001-07-11
DateModified2021-06-02

Ontological Relatives

GenesBIN1

GO terms

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GOName
GO:0002020 protease binding
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006897 endocytosis
GO:0006997 nucleus organization
GO:0007010 cytoskeleton organization
GO:0008021 synaptic vesicle
GO:0008333 endosome to lysosome transport
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016032 viral process
GO:0019828 aspartic-type endopeptidase inhibitor activity
GO:0030018 Z disc
GO:0030100 regulation of endocytosis
GO:0030276 clathrin binding
GO:0030315 T-tubule
GO:0030424 axon
GO:0030425 dendrite
GO:0030838 positive regulation of actin filament polymerization
GO:0031674 I band
GO:0031982 vesicle
GO:0033268 node of Ranvier
GO:0033292 T-tubule organization
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043194 axon initial segment
GO:0045664 regulation of neuron differentiation
GO:0048156 tau protein binding
GO:0048711 positive regulation of astrocyte differentiation
GO:0051015 actin filament binding
GO:0051087 chaperone binding
GO:0051647 nucleus localization
GO:0060987 lipid tube
GO:0060988 lipid tube assembly
GO:0061024 membrane organization
GO:0070063 RNA polymerase binding
GO:0086091 regulation of heart rate by cardiac conduction
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1902430 negative regulation of amyloid-beta formation
GO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1903946 negative regulation of ventricular cardiac muscle cell action potential
GO:1904878 negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Endosome
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR003005 AmphiphysinFamilyFamily
IPR003023 Amphiphysin 2FamilyFamily
IPR004148 BAR domainDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR035471 Amphiphysin 2, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions