Entity Details

Primary name CLD5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00501
EntryNameCLD5_HUMAN
FullNameClaudin-5
TaxID9606
Evidenceevidence at protein level
Length218
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesCLDN5

GO terms

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GOName
GO:0003151 outflow tract morphogenesis
GO:0005198 structural molecule activity
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0007043 cell-cell junction assembly
GO:0007155 cell adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007612 learning
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0016327 apicolateral plasma membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0016525 negative regulation of angiogenesis
GO:0030054 cell junction
GO:0030336 negative regulation of cell migration
GO:0032092 positive regulation of protein binding
GO:0035633 maintenance of blood-brain barrier
GO:0042802 identical protein binding
GO:0043116 negative regulation of vascular permeability
GO:0060021 roof of mouth development
GO:0060325 face morphogenesis
GO:0070160 tight junction
GO:0070830 bicellular tight junction assembly
GO:0120192 tight junction assembly
GO:1903142 positive regulation of establishment of endothelial barrier
GO:1903348 positive regulation of bicellular tight junction assembly
GO:1990963 establishment of blood-retinal barrier
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR003551 Claudin-5FamilyFamily
IPR004031 PMP-22/EMP/MP20/Claudin superfamilyFamilyFamily
IPR006187 ClaudinFamilyFamily
IPR017974 Claudin, conserved siteSiteConserved site

Diseases

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Interactions

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