Entity Details

Primary name CAC1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00555
EntryNameCAC1A_HUMAN
FullNameVoltage-dependent P/Q-type calcium channel subunit alpha-1A
TaxID9606
Evidenceevidence at protein level
Length2506
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCACNA1A

GO terms

Show/Hide Table
GOName
GO:0001540 amyloid-beta binding
GO:0005245 voltage-gated calcium channel activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006816 calcium ion transport
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0008219 cell death
GO:0008331 high voltage-gated calcium channel activity
GO:0016021 integral component of membrane
GO:0019905 syntaxin binding
GO:0034765 regulation of ion transmembrane transport
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0050796 regulation of insulin secretion
GO:0050804 modulation of chemical synaptic transmission
GO:0051899 membrane depolarization
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:1904645 response to amyloid-beta
GO:1904646 cellular response to amyloid-beta

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005448 Voltage-dependent calcium channel, P/Q-type, alpha-1 AFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domainDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00252 PhenytoinDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00653 Magnesium sulfateDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00825 LevomentholDrugbanksmall molecule
DB00836 LoperamideDrugbanksmall molecule
DB01244 BepridilDrugbanksmall molecule
DB06283 ZiconotideDrugbanksmall molecule
DB06446 DotarizineDrugbanksmall molecule
DB09089 TrimebutineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09232 CilnidipineDrugbanksmall molecule
DB09236 LacidipineDrugbanksmall molecule
DB09238 ManidipineDrugbanksmall molecule
DB11093 Calcium citrateDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink