Entity Details

Primary name SDCB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00560
EntryNameSDCB1_HUMAN
FullNameSyntenin-1
TaxID9606
Evidenceevidence at protein level
Length298
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesSDCBP

GO terms

Show/Hide Table
GOName
GO:0002091 negative regulation of receptor internalization
GO:0005109 frizzled binding
GO:0005137 interleukin-5 receptor binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005895 interleukin-5 receptor complex
GO:0005912 adherens junction
GO:0005925 focal adhesion
GO:0006612 protein targeting to membrane
GO:0006930 substrate-dependent cell migration, cell extension
GO:0007268 chemical synaptic transmission
GO:0007346 regulation of mitotic cell cycle
GO:0008093 cytoskeletal anchor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016020 membrane
GO:0030036 actin cytoskeleton organization
GO:0030307 positive regulation of cell growth
GO:0030335 positive regulation of cell migration
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031965 nuclear membrane
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 intracellular signal transduction
GO:0035578 azurophil granule lumen
GO:0042327 positive regulation of phosphorylation
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045545 syndecan binding
GO:0046330 positive regulation of JNK cascade
GO:0046982 protein heterodimerization activity
GO:0047485 protein N-terminus binding
GO:0048013 ephrin receptor signaling pathway
GO:0060544 regulation of necroptotic process
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:1903543 positive regulation of exosomal secretion
GO:1903553 positive regulation of extracellular exosome assembly
GO:1903561 extracellular vesicle

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Endoplasmic reticulum membrane
Melanosome
Membrane raft
Nucleus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR030528 Syntenin-1FamilyFamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SDCB1_HUMANPDC6I_MOUSEIntAct22660413 details
SDCB1_HUMANSOX4_MOUSEI2D21986941 details