Entity Details

Primary name ACKR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00590
EntryNameACKR2_HUMAN
FullNameAtypical chemokine receptor 2
TaxID9606
Evidenceevidence at protein level
Length384
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesACKR2

GO terms

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GOName
GO:0004950 chemokine receptor activity
GO:0005044 scavenger receptor activity
GO:0005654 nucleoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007275 multicellular organism development
GO:0009897 external side of plasma membrane
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0031965 nuclear membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0055037 recycling endosome
GO:0060326 cell chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome
Recycling endosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR001277 CXC chemokine receptor 4/atypical chemokine receptor 2FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR033037 Atypical chemokine receptor 2FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ACKR2_HUMANCCL3_MOUSEBioGRID9405404 details
ACKR2_HUMANCCL2_MOUSEBioGRID9405404 details