Entity Details

Primary name SH2B2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14492
EntryNameSH2B2_HUMAN
FullNameSH2B adapter protein 2
TaxID9606
Evidenceevidence at protein level
Length632
SequenceStatuscomplete
DateCreated2003-08-15
DateModified2021-06-02

Ontological Relatives

GenesSH2B2

GO terms

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GOName
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007596 blood coagulation
GO:0008286 insulin receptor signaling pathway
GO:0035556 intracellular signal transduction
GO:0035591 signaling adaptor activity
GO:0042169 SH2 domain binding
GO:0050851 antigen receptor-mediated signaling pathway
GO:0050853 B cell receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015012 Phenylalanine zipperDomainDomain
IPR030520 SH2B adapter protein 2FamilyFamily
IPR030523 SH2B adapter proteinFamilyFamily
IPR035058 SH2B2, SH2 domainDomainDomain
IPR036290 Phenylalanine zipper superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink