Entity Details

Primary name BHE40_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14503
EntryNameBHE40_HUMAN
FullNameClass E basic helix-loop-helix protein 40
TaxID9606
Evidenceevidence at protein level
Length412
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesBHLHE40

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007623 circadian rhythm
GO:0009952 anterior/posterior pattern specification
GO:0016604 nuclear body
GO:0019904 protein domain specific binding
GO:0032922 circadian regulation of gene expression
GO:0042752 regulation of circadian rhythm
GO:0042803 protein homodimerization activity
GO:0043153 entrainment of circadian clock by photoperiod
GO:0043425 bHLH transcription factor binding
GO:0043426 MRF binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046982 protein heterodimerization activity
GO:0050767 regulation of neurogenesis
GO:0070888 E-box binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003650 Orange domainDomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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