Entity Details

Primary name CD8A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP01731
EntryNameCD8A_MOUSE
FullNameT-cell surface glycoprotein CD8 alpha chain
TaxID10090
Evidenceevidence at protein level
Length247
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCd8a

GO terms

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GOName
GO:0002456 T cell mediated immunity
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0023024 MHC class I protein complex binding
GO:0042110 T cell activation
GO:0042802 identical protein binding
GO:0044853 plasma membrane raft
GO:0045065 cytotoxic T cell differentiation
GO:0050850 positive regulation of calcium-mediated signaling
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015468 CD8 alpha subunitFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions