Entity Details

Primary name SOCS6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14544
EntryNameSOCS6_HUMAN
FullNameSuppressor of cytokine signaling 6
TaxID9606
Evidenceevidence at protein level
Length535
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesSOCS6

GO terms

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GOName
GO:0001772 immunological synapse
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0006952 defense response
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0009968 negative regulation of signal transduction
GO:0010498 proteasomal protein catabolic process
GO:0016567 protein ubiquitination
GO:0019221 cytokine-mediated signaling pathway
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0043687 post-translational protein modification
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity
GO:0050868 negative regulation of T cell activation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001496 SOCS box domainDomainDomain
IPR028421 Suppressor of cytokine signalling 6FamilyFamily
IPR035865 SOCS6, SH2 domainDomainDomain
IPR036036 SOCS box-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR037345 SOCS6, SOCS box domainDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink